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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c169f7919bccfdf0eefc6613fce3b9e8d3262bd98d4b4f66f33bf18a6782183d' 
  AND token = 'zn0NgN2qKdHdDUKFDg3tBMMST0MbPtHUmkoKnNTwgMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}