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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1da361e42a2bb107df228d56e576be30700a365807b4266773c8952eadd76bf5' 
  AND token = 'n4ex5xqgF2xhQpWoOfk+xrEImbYCW4Y6TWtnIkJcfes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}