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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '201ddf2a5d0fa7091e44512d7c509579808dc44f11b307e8b997c698bebe9643' 
  AND token = 'jhhQ5CJvgm9fvvzHTSFU4BhqMpZn5aRt49e9HXAWybo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}