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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a744f5c65ab02a352b3aaeee4eded58feea7eade8f887237cf14e62e9eb3382' 
  AND token = 'cw8hU5Dypthv3J0dQ5ltQWtgLiCXKB65t+x/X3Qmrhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}