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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3af8171b162bd1b07e5ce49250d9e0880ad3782828cf072d7648fb42bf03f0e9' 
  AND token = 'Z1OofGaCoMPqw9WprZu2TZtMddXNgq9S8EYHCLBh8ps=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}