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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bc0197e7bb3645c2fb4e179907a12f3a6313bd6d59c55661955bf191d90724' 
  AND token = 'BxWJbCc1gGCvQnvhcFqGq5F5deE3HrVVNVUN2Icvl+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}