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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a08d8467163a7819b4aa1964339a77b63b94c9826cfb4914d200a2e9f738dea' 
  AND token = 'YmFlfe9FdjURzSU64SlyXfRsiSTabNKf2+DLsx9eX6I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}