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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2162199c30680850b08ed7cba789a6dfe68c0a9b91b6ee34e7a99a85205d4a5d' 
  AND token = 'y2H3DJpIj1O86JJU2oIVZG8LHFYms3hBUjSUd9IM0PM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}