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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3046888ea6713d88b74581756bca3236b1ac45a451afe53b32a718401a3a7a78' 
  AND token = 'T7NXPO52zsOC9Oj21iu7qZM8P3XmaUINYSvKZVDm20s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}