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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45f18152a842bb95b1221106457f443ef9333c7449d13ff5bc8ee1212f1314f9' 
  AND token = 'Cv6GrmNzi0jA8tp7v0MAP8kzQYLi6gGxjUxz72Ezd9I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}