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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0538d94e069a3c855371187cb2e7c3c35ac5cf085b289586534d5049134c070a' 
  AND token = 'W1eQ4m5zAS2S9u1sPgPFau5m7MhDKGnzURZgFe+/VZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}