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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de75f370e2c33e7dc9bddf9b175d504ad482b43a145e7bd7f8ec1b498945d051' 
  AND token = '4uuKlJxP+/7l8Xo6YYgrSoLVTHoCSr7dBJhA8I4oslU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}