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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c27bf1bc87369eef4af6c8b7a75d65a1f552baa67ead11620a5124c46ec6f55c' 
  AND token = 'VThgg6cIlz+SoE7ZL7btsxBG2BB4w7CMZg5TIins3M0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}