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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a289704410f61b6dd3494af87d37695608edd32f1801b8d7c3be5aaf0b1cb08c' 
  AND token = 'NnZtJjYdYc+PwRM2RaWSkB6LGCY9u0Q5MquhfAjaof4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}