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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cfaab9a39887d42a480b5b2f77c64354d1df9d27160217dd496dbec1f5c3199' 
  AND token = '22ErlksGhzTLRxU17T8U6ZaVSsN12HuVxk/a+hPFT3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}