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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c9b7572a305a1999c12b276d386923230affe1506b2996b7bc8f32cf1461d63' 
  AND token = 'imIGAnjHOCTM4nzRx+4wXkV4jk+tI2Mlc5a8PWQqPnE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}