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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9473549ae6488b822e5336aee51d4d475fac19c2d84db642cdf335d4c97dfa7b' 
  AND token = '2K4yzCuF+AbHt6RcDJ0CcIdwIbJ4PAQO0iL1Zg7cIBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}