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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6d6ebee4760c58b9aa83017449dc60807b7cb766a847d159dc76acf99fa4d60' 
  AND token = 'rHqS2R22jlFgDFEQmUJd7tODTScnGl7kokjSDVo5E9E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}