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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df356376e0f80a17a857686fb62ce37da285741ff70d313575b76bdac7a044ac' 
  AND token = '+w07+zvMioxbSat4lRyJbfDws+3Qk9ooT2e1Y2fnHWY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}