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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db6fb6e419bd8fbb352a0e05ad164eb631d5f54bb05f210c252e02e94344db74' 
  AND token = '+HMVEHlr4SFWU74xOtASTmIdDYvfQqlZsSv39fnibZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}