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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f95b33cde303a05cb1371dff44bdd18a32e3c6be33c487724b464cda7e81888' 
  AND token = 'zop6V9bI5uQoYLvI/qeveOOEEJ9E3Ko/D+RL4NZfbp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}