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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3ec7baaf5ae8e36bd18886edac9251336503b1f8f2c299c34b6690aa444b366' 
  AND token = 'fszl8+kUsLOlZ6WPcjSs+bev8HozgQG6v/tYq8Hx69U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}