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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b670386e497071b7c9d5a996afacd7075374e391031c03ea2aac74b238218e0' 
  AND token = 'Hv0Z2Jj3aIspcw0rFN511QuKo+R2EdL322cbaSKBWbU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}