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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e0ccf64656da0e095531953eb7df15036fb980eb93f4e2d3aab4b1c133f490a' 
  AND token = 'VtYxcJ4Z2/W+ZzE8g0JncAUMoJRSp7weAcU60DcCUBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}