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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1b586bfd4bd59c8c1b33dbc57052b0a4afa5b23f8ba8c84e1c70565df449149' 
  AND token = 'zK0nwzi1kmQEqU5/93tq5TRuCjTNww6RD97OwXehyBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}