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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44bbc48413056a6c8a81cc26b01485bf1c44d06db7f82b7019fd305e722d0424' 
  AND token = 'yzjF6ZdLWl7HOV06vcZCXIPmticBmtR2R0Is4qESX8I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}