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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'abc1d8b2f4db9db2dee952f75cfc82ae67e2477e1bc362f7020df6719d20049f' 
  AND token = 'RhtCn17+K12MHTEh8TGPbUerc/W5/p4iucDmPrJJLmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}