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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6420257f3ee0518b46db7d335f22472f56b36f3d5ad2e6bc2e8d2c39cf16c93a' 
  AND token = 'ZV6xAKmlTKszGj9Wy/aMd+2xcny0d7CoER43NCY2Fmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}