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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd016f8375befd432292c48c66f40ada800ecb4e9874fe20c9c2bfba5e1342df8' 
  AND token = 'gS+LOaQf8w024tii5ShCYH0XZfbgZOfTu0bu9vfpSKM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}