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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18e5d0e4930a6ab2750e06514eb5565a8fff2dbb02a2f4ee5b957c93ca020760' 
  AND token = 'xw/Z7AxFl3n4QgSrKYZsiA3QupB0yYIpPzZKkjPL/dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}