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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0cb373623edb56e061fae850bb9edfd708f8ac24904b68ff545725318f2cb771' 
  AND token = 'gZLts+raDd596Nqx/c3/YCYkP/EpTg7NQdMEBNbn5HI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}