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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e644e54feb8abc2d5371eeff2cf3bc0d83b089c31bdf952decd349ed5719f3ee' 
  AND token = '8WEsH3wK13TnYltnREeb6501tIYSXGOV622Y/veeKWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}