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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea09b7b2bc6fd2f167057efee1813c881fc1a5a6dc2de1a990699f700feed246' 
  AND token = 'ZWZ1Fn5xT5IelR5Qa9mWYtOqYBSfnwSAFIsJSajILX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}