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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fc8f018d814033e84bd8be19b8d5b4435fe03634f75a867ec4260b8b3b8ed87' 
  AND token = 'IBe1CNYatgwUpi+UY93ohND5gBM81BgMfxAFlUZEdy4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}