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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ca0105a866ce3b9d416618c25f8c62b2f05b16053385ae0e895b2dfbd95cad8' 
  AND token = 'QPYe0n+nMS0XD873QWhM2QtXM+oz+PKZN9AdDaNQE2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}