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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59368e6b3c969b01b339755a6fea82c3de69b44111e645015258978072eb4b42' 
  AND token = 'rzVNeicKdpJ3rZmEZaUd6c0yizYUMrcEZJJVlsvBOjk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}