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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00bd52a3f837e2ca308c6d484de3538971ffaffb3cfac9b97b6608fcc0b56a42' 
  AND token = 'H4uv1dlvhMGbPRQkSU4GmbnYwPJsXEotCcnl5M3iHvc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}