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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50fdb96d1bbe8b2c9dd7d2e009cf9a5251ae47ab9c2b347ac7b1edc25b761aee' 
  AND token = '/3Pd4Gap28iuDV9IIfMnMxP3qSwv8QbkNd6Ze21tHqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}