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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fb622c537dc64ff73b22143a332c4176354f0acb3e35b04129f90189720500c6' 
  AND token = '3gPb69iKRsOEfDtC1zUqeKTXIG1VGqsjUMaj52XCO7M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}