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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fd5369e2067e5b611184bbbc220542f3d8d472f665c90d4f1dbf33d828ca468' 
  AND token = '2sep7xmVugj5JO8eI4groTIROdjQENuv2/pS9uS47M8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}