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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67de39f62a8b6555005490046578f1ad2caa086def683cf4236f4988a652b7d8' 
  AND token = '0+FPzopv6iPAfibrwwAKnN09u5YjOt6s4dIbDRSXDeQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}