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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eaf5946aa0854289defb45f2ca25af8de606c330679c89992b4e6fe3a25e6571' 
  AND token = 'rB7S5av2it1ukv2iUyVTmnYcGAQMyblDvYO1vj21OYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}