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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b52b144c4774576998c255d9e54735a570f1b2ff472e4cb67c23dd625568ee9' 
  AND token = 'qGJpL8u3ZcsyrTGrvb2z2oqGqrRS5HHiSNTCJsvUQR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}