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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed300ac51351883dfe5e8de03943dc2b30373f763cf9caad98017c3163047788' 
  AND token = '9qTvc8VThFjy28ECNNO+tHk2OJIjQHN3NEuKJoFg4Rw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}