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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aabe08695f7038ca33bd5ee3eff747ca39a85df5dc930ad0b3210aa3a5f7dd03' 
  AND token = 'GRscmGuWj4+lSRSG3mjp6nWqspQlo3uaevKJl2N8jBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}