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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f738aff6ac1e12fe1f2a876a15b6a224874913c67525b40774781deeb5a442a' 
  AND token = 'bYjZKKkkL2A7w6EVQro3zSjy3748wPcGVfym/S0s4Zc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}