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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '716ccd182bcfe410ff345f33179c597818a2de64713d8910ee205e40acf3f6a6' 
  AND token = 'an+GzrJcX0oO3FR8qf2y0EgN7vtgWYpEGm4cQ55+yVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}