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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4945413949cb85dab62ba0bbc5605ff9a00970e02c1b27dbbb453cae689a3b2a' 
  AND token = 'hTGS+AnJOV41Xo/Xl18CTlgc5JwkbIt4vnLHKi8tIUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}