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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e55f932d50ab08d52daf0a9a047542d2581371e5f8319cd76c8bc6f8a6f17bb' 
  AND token = '6ymlgF7MaBLr9fos6lnb1pu+GCFjFS0y1ENvKkjSDmw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}