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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '746e8f5c22e32e2a4ad165d0ea9d1b8c45a4f27423f3533bf74cb375e3d6308c' 
  AND token = 'q/pMbGv8PnzacyAFag2/ojFfhZxP+vX9rCjaf9OG12c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}